Basic Information
| Dataset | GSE235448 |
|---|---|
| Status | 2023-08-21 |
| Species | Homo sapiens |
| Source | NCBI GEO |
| Subcellular Localization | nucleus|cytosol |
| PMID | 37566088 |
| Title | Profiling nucleo/cytoplasmic distribution of mRNAs identifies a role for the Golgi-to-ER trafficking in C9orf72 toxicity |
| Citation | Rossi S, Di Salvio M, Balì M, De Simone A et al. C9orf72 Toxic Species Affect ArfGAP-1 Function. Cells 2023 Aug 5;12(15). |
| Experimental Design | Gene expression profiling analysis of nuclear and cytoplasmic fractions from HeLa cells expressing a mock plasmid (control) or an expanded (G4C2)31 RNA repeat. A total of n=12 samples from n=3 independent experiment were analysed by RNA seq: n=3 nuclear and n=3 cytoplasmic control samples; n=3 nuclear and n=3 cytoplasmic G4C2 samples. |
Sample Information
| BioProject | Sample Name | Localization | Genotype | Source | Label |
|---|---|---|---|---|---|
| PRJNA986091 | GSM7502518 | nucleus | mock | HeLa cells | HeLa, mock, nucleus, biol rep 1 |
| PRJNA986091 | GSM7502519 | nucleus | G4C231 | HeLa cells | HeLa, G4C231, nucleus, biol rep 1 |
| PRJNA986091 | GSM7502520 | cytosol | mock | HeLa cells | HeLa, mock, cytosol, biol rep 1 |
| PRJNA986091 | GSM7502521 | cytosol | G4C231 | HeLa cells | HeLa, G4C231, cytosol, biol rep 1 |
| PRJNA986091 | GSM7502522 | nucleus | mock | HeLa cells | HeLa, mock, nucleus, biol rep 2 |
| PRJNA986091 | GSM7502523 | nucleus | G4C231 | HeLa cells | HeLa, G4C231, nucleus, biol rep 2 |
| PRJNA986091 | GSM7502524 | cytosol | mock | HeLa cells | HeLa, mock, cytosol, biol rep 2 |
| PRJNA986091 | GSM7502525 | cytosol | G4C231 | HeLa cells | HeLa, G4C231, cytosol, biol rep 2 |
| PRJNA986091 | GSM7502526 | nucleus | mock | HeLa cells | HeLa, mock, nucleus, biol rep 3 |
| PRJNA986091 | GSM7502527 | nucleus | G4C231 | HeLa cells | HeLa, G4C231, nucleus, biol rep 3 |
| PRJNA986091 | GSM7502528 | cytosol | mock | HeLa cells | HeLa, mock, cytosol, biol rep 3 |
| PRJNA986091 | GSM7502529 | cytosol | G4C231 | HeLa cells | HeLa, G4C231, cytosol, biol rep 3 |
Subcellular Localization Number
RNA Type:
Condition:
Localization Differential Analysis
RNA Type:
Localization:
Condition:
Method:
Enrichment:
Specific Subcellular Localization
RNA Type:
Method:
Dynamic RNA Localization
RNA Type:
Method:
Specific Enrichment Analysis
RNA Type:
Localization:
Condition:
Method:
Enrichment:
Specific RNA Ratio
RNA Type:
RNA Symbol:
TPM:
